Clinical Trials

Clinical Trials

To fulfill our passion for clinical research, Advanced Neurology of Colorado has a research counterpart, Advanced Neurosciences Research, LLC. 

Together, the research team participates in over 15 clinical trials, including those listed below. All trails noted below are active at this time and we are currently enrolling participants. Please sign up below for more information on the trials and/or how to participate.

For additional information, please visit http://www.clinicaltrials.gov

Clinical Research Interest Submission

To receive communication about currently enrolling or future studies, please enter your full name and best contact method below. You do not have to be a current patient with Advanced Neurology in order to submit your response.

Multiple Sclerosis Trials

 

EFC17919

Efficacy and Safety Studies of Frexalimab (SAR441344) in Adults With Relapsing Forms of Multiple Sclerosis (FREXALT)

Master Protocol of Two Independent, Randomized, Double-blind, Phase 3 Studies Comparing Efficacy and Safety of Frexalimab
(SAR441344) to Teriflunomide in Adult Participants With Relapsing Forms of Multiple Sclerosis

https://clinicaltrials.gov/study/NCT06141473

 

EFC17504

Efficacy and Safety Study of Frexalimab (SAR441344) in Adults With Nonrelapsing Secondary Progressive Multiple Sclerosis (FREVIVA)

A Randomized, Double-blind, Phase 3 Study Comparing Efficacy and Safety of Frexalimab (SAR441344) to Placebo in Adult Participants With
Nonrelapsing Secondary Progressive Multiple Sclerosis

https://clinicaltrials.gov/study/NCT06141486

 

20230309

Comparison Between ABP 692 and Ocrevus® (Ocrelizumab)

A Randomized, Double-blind, Parallel-group Study to Compare Pharmacokinetics, Pharmacodynamics, Clinical Effects, and Safety Between ABP 692 and Ocrevus® (Ocrelizumab) in Subjects With Relapsing-remitting Multiple Sclerosis

https://clinicaltrials.gov/study/NCT06700343

 

TG1101-RMS401

Study to Evaluate Efficacy of a Modified Regimen of Ublituximab (ENHANCE)

Evaluating Efficacy of a Modified Regimen of Ublituximab

https://clinicaltrials.gov/study/NCT05877963

 
TG1101-RMS406

A Study Evaluating the Real World Experience of Participants Treated With BRIUMVI® (Ublituximab-xiiy) for Relapsing Multiple
Sclerosis (RMS) (ENABLE)

REal World ExperieNce With BRIUMVI® (UblituximAB-xiiy) Treated Patients: A Longitudinal REgistry Study (ENABLE)

https://clinicaltrials.gov/study/NCT06433752

 

 

Migraine Trials

 

CLIN-10200-454

A Study to Evaluate IPN10200 Safety and Efficacy in the Prevention of Episodic or Chronic Migraine in Adults (MERANTI)

A Multicentre, Randomised, Double-blind, Placebo-controlled, Dose Escalation and Dose Finding Phase II Study to Evaluate the Safety and
Efficacy of IPN10200 in the Prevention of Episodic or Chronic Migraine in Adults

https://clinicaltrials.gov/study/NCT06625060

 

20668A

A Trial of Eptinezumab in Participants With Migraine and Insufficient Response to Anti-CGRP Medications

Interventional, Open-label Trial, Investigating the Effectiveness of Eptinezumab in Participants With Migraine and Previous
Inadequate Response to CGRP-targeting Therapies

https://clinicaltrials.gov/study/NCT06625060

 

C4951009

Efficacy and Safety Study of Rimegepant for the Preventative Treatment of Migraine in Pediatric Subjects

A Phase 3, Randomized, Double-blind, Placebo-controlled Study to Evaluate the Efficacy and Safety of Rimegepant in Migraine Prevention
in Children and Adolescents ≥ 6 to <18 Years of Age

https://clinicaltrials.gov/study/NCT05156398

 
 
M21-201(and roll-over open label M21-199)

A Study to Assess the Adverse Events and Change in Disease Activity of Oral Atogepant Tablets in Pediatric Participants (6-17
Years of Age) With Episodic Migraine (ATO EM PEDS)

A Phase 3, Multicenter, 12-Week, Double Blind, Placebo-Controlled Study to Evaluate the Safety and Efficacy of Atogepant for
the Preventive Treatment of Episodic Migraine in Pediatric Subjects 6-17 Years of Age.

https://clinicaltrials.gov/study/NCT05711394