Myasthenia Gravis

Myasthenia Gravis: What Is It, Causes, Symptoms & Treatments

Myasthenia Gravis (MG) is a chronic autoimmune neuromuscular disorder that causes weakness in the body’s voluntary muscles—those we can consciously control. It occurs when the immune system produces antibodies that block or destroy communication between nerves and muscles, leading to fatigue and difficulty with basic movements like speaking, swallowing, or keeping the eyes open.

While Myasthenia Gravis can affect anyone, it most often develops in adult women under 40 and men over 60. The condition is not inherited or contagious. In most cases, it develops when antibodies interfere with acetylcholine receptors at the neuromuscular junction, preventing proper muscle contraction. In some people, a tumor or enlargement of the thymus gland may also play a role in triggering the disorder.

While there is no known cure, modern treatments—including medications, plasma exchange, intravenous immunoglobulin (IVIG), and in some cases, surgery—can effectively control symptoms and help patients maintain a high quality of life.

Our neurologists have extensive experience in diagnosing and treating Myasthenia Gravis. Our team is dedicated to providing you with the specialized treatment and compassionate care you need.

How We Care for Myasthenia Gravis

At Advanced Neurology of Colorado, our approach to Myasthenia Gravis care begins with a detailed evaluation to determine your specific type of MG, ocular or generalized, and then tailors your treatment based on severity, overall health, and response to previous therapies.

Our treatment options may include:

  • Medication management, such as cholinesterase inhibitors (like pyridostigmine) to improve communication between nerves and muscles, and immunosuppressants to reduce antibody activity.
  • Infusion therapies which can quickly reduce harmful antibodies in the bloodstream and relieve severe symptoms.
  • Thymectomy, when appropriate, to remove the thymus gland and help prevent further immune attacks on muscle receptors.

Because Myasthenia Gravis can fluctuate in intensity, our neurologists provide ongoing monitoring and care adjustments to ensure stability and minimize complications.

Sarah Yang, MD
Board-Certified Neurologist

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Whether you're newly diagnosed, looking for a second opinion, or just want to learn more about us, someone from our team can reach out to you to share more information about Advanced Neurology of Colorado.

Note: This form is for new patients or referring providers only. If you are a current patient, please call us at  970-226-6111

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Courtney P.
Patient

Dr. Dasari has been a God-send for my MS. He is incredibly knowledgeable and makes me feel heard. He allocates his time for me as a patient and I know I couldn’t manage this disease without him!

Frequently Asked
Questions

What is Myasthenia Gravis?

MG is a chronic autoimmune disorder where antibodies block or destroy neuromuscular junction receptors, leading to muscle weakness. This weakness tends to worsen with repeated activity and improves with rest, which helps distinguish MG from other neurological conditions.

What causes Myasthenia Gravis? Myasthenia Gravis is not inherited or contagious. It generally develops later in life when the immune system mistakenly attacks the body’s own acetylcholine receptors on muscle cells, interfering with muscle contraction. In some cases, temporary Myasthenia Gravis can occur in newborns when antibodies from a mother with MG pass through the placenta, but symptoms usually disappear within a few weeks after birth.

What are the main symptoms of MG?

Early signs of Myasthenia Gravis often start with eye-related symptoms such as drooping eyelids (ptosis) or double vision (diplopia). As the disease progresses, patients may notice weakness in the face, neck, arms, or legs, as well as trouble swallowing, chewing, or speaking clearly. In generalized Myasthenia Gravis, symptoms can affect multiple muscle groups, while ocular Myasthenia Gravis typically remains limited to the eyes.

MG often progresses gradually, though symptom intensity can fluctuate from day to day. “End-stage” MG is rare thanks to effective modern treatments. However, late-onset MG may appear more suddenly and require ongoing management to prevent complications such as breathing difficulty or aspiration.

How is MG diagnosed?
  • Diagnosing Myasthenia Gravis involves a combination of clinical exams and specialized testing. Your neurologist may order:
    • Blood tests to detect acetylcholine receptor (AChR) or muscle-specific kinase (MuSK) antibodies
    • Electromyography (EMG) to measure the electrical activity between nerves and muscles
    • Edrophonium (Tensilon) test to assess immediate muscle response
    • CT or MRI scans to check for thymus abnormalities or thymoma
    At Advanced Neurology, our neurophysiology team uses advanced EMG testing and antibody panels to confirm diagnosis and determine the most effective treatment approach.
What treatments help manage MG?

There is no cure for Myasthenia Gravis, but treatments can effectively control symptoms and improve muscle strength. The best plan depends on your age, overall health, and severity of symptoms.Common options include:

  • Medications: Cholinesterase inhibitors (Mestinon), immunosuppressants (prednisone, azathioprine)
  • Plasmapheresis or IVIG (for severe cases)
  • Thymectomy (surgical removal of the thymus gland if needed


Most people with Myasthenia Gravis live active, fulfilling lives with proper treatment and lifestyle adjustments. Managing MG often involves balancing medication schedules, avoiding overexertion, reducing stress, and preventing infections that could trigger flare-ups.

Complications like Myasthenic Crisis—severe muscle weakness that affects breathing—are rare but require emergency care. With consistent medical follow-up and personalized treatment, patients can maintain normal life expectancy and stable symptom control.

Can MG go into remission?

Yes, some patients experience remission with treatment, especially after thymectomy.

Is MG life-threatening?

In rare cases, myasthenic crisis (severe breathing difficulty) can occur, requiring emergency care.

We are in-network with all major insurance plans in Northern Colorado. Call our office if you have a question about your specific insurance plan.
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Toogether logoToogether logoToogether logoAriseHealth logoOE logo2020INC logoThe Paak logoEphicient logoToogether logoToogether logoToogether logo
Toogether logoToogether logoToogether logoAriseHealth logoOE logo2020INC logoThe Paak logoEphicient logoToogether logoToogether logoToogether logo