Peripheral neuropathy refers to nerve damage, often causing numbness, tingling, or pain in the hands and feet.

Diabetes (most common cause)

• Vitamin deficiencies (B12, folate)

• Alcohol abuse

• Autoimmune diseases

• Vein disease (chronic venous insufficiency)

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Poor circulation from vein disease (varicose veins, deep vein thrombosis) can lead to nerve damage due to reduced oxygen and nutrient supply.

• Medications: Pain relievers (gabapentin, duloxetine)

• Lifestyle changes: Blood sugar control, compression stockings

• Physical therapy & exercise

• Vein procedures: Sclerotherapy, laser therapy

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Early treatment (e.g., controlling diabetes) may improve symptoms, but severe nerve damage is often permanent.

Chronic vein diseases (like varicose veins, chronic venous insufficiency, or deep vein thrombosis) can impair blood circulation, leading to reduced oxygen and nutrient supply to nerves. Over time, this can contribute to nerve damage (neuropathy), causing symptoms like pain, tingling, and numbness—especially in the legs.

• Physical exam (checking for varicose veins, swelling)

• Doppler ultrasound (to assess blood flow)

• Nerve conduction studies (NCS) / EMG (to confirm neuropathy)

• Blood tests (to rule out diabetes, vitamin deficiencies)

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Look for:  

• Leg heaviness, swelling, or aching

• Visible varicose or spider veins

• Skin changes (darkening, ulcers, or thickening near ankles)

• Worsening neuropathy symptoms when standing or sitting for long periods

• Exercise regularly (walking, swimming—improves circulation)

• Elevate legs when resting to reduce swelling

• Wear compression stockings (if recommended)

• Avoid prolonged sitting/standing

• Maintain a healthy weight (reduces vein pressure)

See a vascular specialist or neurologist if you have:

• Persistent leg pain, swelling, or visible vein issues

• Numbness/tingling that worsens with standing

• Non-healing wounds or skin changes