Briumvi

What is Briumvi®?

Briumvi® (ublituximab-xiiy) is a monoclonal antibody approved for the treatment of relapsing forms of multiple sclerosis (MS) in adults. It is part of the anti-CD20 therapy class, designed to target and deplete B cells — key players in the immune system’s attack on the nervous system in MS.Briumvi® offers a convenient and effective option for patients needing B-cell depleting therapy, featuring a shorter infusion time to enhance both treatment efficiency and patient experience.

How does Briumvi® work?

In multiple sclerosis (MS), the body’s own immune system mistakenly attacks the myelin sheath — the protective covering around nerve cells in the brain and spinal cord. One type of immune cell involved in this process is called a B-cell, which carries a marker called CD20 that helps identify it.

When the myelin sheath gets damaged, the nerve cells can’t communicate properly, leading to problems with movement, speech, balance, vision, and even bowel function over time.

While Briumvi is not a cure for MS, it works by targeting the CD20 marker on B-cells, helping to destroy them before they can cause more damage. This helps to calm the immune system and slow down the progression of the disease.

How much does Briumvi® cost?

Briumvi® cost can vary depending on several factors including insurance status and insurance provider. Our team at Advanced Neurology of Colorado are committed to lowering costs and improving access for our patients.

We work with virtually all leading commercial insurance providers in the greater Intermountain region, including Aetna, Anthem, Blue Cross Blue Shield, Cigna, DMBA, EMI Health, Humana, PEHP Health & Benefits, Select Health, as Tricare, as well as Medicaid and Medicare.

We’re here to make treatment more affordable and less stressful. Our team takes care of prior authorizations and benefits verification for you, and we’ll personally guide you through copay assistance and foundation support programs to help lower your out-of-pocket costs.

Why Patients Choose Advanced Neurology of Colorado's Infusion Center to Receive Their Briumvi® Infusion:

Clinical Excellence and Neurological Expertise

Our infusion center is proud to have a board-certified neurologist on-site, along with a team of BSN-prepared and Registered Nurses that specialize in infusion care for neurological conditions, all committed to delivering the highest standard of care for our patients.

Lower Costs and Financial Assistance

We handle prior-authorization, benefits verification, and guide patients through copay assistance and foundation programs to reduce out-of-pocket costs. Additional financial help may be available if you qualify — just ask, and we’ll help you explore every option.

A Cigna report recently found that with a physician-owned infusion site, like Advanced Neurology of Colorado's Infusion Center, patients see much lower out-of-pocket and overall costs than they would at a hospital outpatient infusion center.

Established leader in MS & Neurological care

35+ years in the Intermountain region, serving thousands of individuals with MS and other neurological disorders.

Learn more about Infusion Therapy at ANC

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Important Info

Referral Form:
Briumvi
What It Treats:

Multiple Sclerosis

FDA Approval:

Briumvi® (ublituximab-xiiy): Approved in December 2022

Manufacturer:

TG Therapeutics, Inc.

What Our Patients Have to Say

"Easy parking, wheelchair-friendly, and a coffee bar in the waiting area."

Aisha B.

"The MA Jess noticed I was anxious and brought me a weighted blanket. Above and beyond!"

Rachel L.

“Amazing. I have been with other Doctors at this practice as well but I had an amazing experience with Dr. Lackey specifically. Very attentive and friendly to work with! Highly recommend!”

Payton E.

"Modern, clean, and calming—especially the infusion center with mountain views."

David M.

"ALS guardian - Coordinates with my pulmonologist, PT, and speech therapist in one shared portal. Her ALS Functional Rating Scale checks keep us proactive."

Thomas W.

"Billing is transparent—no surprise charges like at my last neuro."

Daniel R.

“Dr. Dasari has been a God-send for my MS. He is incredibly knowledgeable and makes me feel heard. He allocates his time for me as a patient and I know I couldn’t manage this disease without him!”

Courtney P.

"MG crisis hero - Got me into the hospital for IVIG within 4 hours during a bulbar crisis. Her fellow (Dr. Patel) even checked on me at midnight."

Diane K.

"Migraine magician - Botox + Nurtec combo cut my headache days from 25/month to 4. His headache diary app makes tracking effortless."

Priya N.

"Brutally honest - Wish she'd sugarcoat less, but her MG treatment plan stopped my hospitalizations. Clinical trials access is a plus."

Patient

"ANC’s telehealth option saved me a 2-hour drive. Seamless tech setup!"

Sophia K.

“Dr. Yang is nothing but amazing! She has helped me so much with a diagnosis that moved my world upside down. She treats my almost daily migraines as well. She and her team will do what they can to get me the medication I need! She is very compassionate and kind!”

Courtney B.

"The only neurology clinic I’ve been to where you don’t feel like just a number."

Linda H.

"ANC runs like a well-oiled machine. Appointments start on time, and the staff remembers me every visit."

Robert P.

"No-nonsense - Wish visits were longer, but his neuropathy staging system helped us prioritize treatments."

Carlos J.

"Spotless floors, sanitizer everywhere, and masks required. Felt very safe."

Mark J.

“Amazing. I have been with other Doctors at this practice as well but I had an amazing experience with Dr. Lackey specifically. Very attentive and friendly to work with! Highly recommend!”

Payton E.

"No-nonsense - Wish visits were longer, but his neuropathy staging system helped us prioritize treatments."

Carlos J.

"Migraine magician - Botox + Nurtec combo cut my headache days from 25/month to 4. His headache diary app makes tracking effortless."

Priya N.

“Dr. Dasari has been a God-send for my MS. He is incredibly knowledgeable and makes me feel heard. He allocates his time for me as a patient and I know I couldn’t manage this disease without him!”

Courtney P.

"Brutally honest - Wish she'd sugarcoat less, but her MG treatment plan stopped my hospitalizations. Clinical trials access is a plus."

Patient

"MG crisis hero - Got me into the hospital for IVIG within 4 hours during a bulbar crisis. Her fellow (Dr. Patel) even checked on me at midnight."

Diane K.

"ALS guardian - Coordinates with my pulmonologist, PT, and speech therapist in one shared portal. Her ALS Functional Rating Scale checks keep us proactive."

Thomas W.

“Dr. Yang is nothing but amazing! She has helped me so much with a diagnosis that moved my world upside down. She treats my almost daily migraines as well. She and her team will do what they can to get me the medication I need! She is very compassionate and kind!”

Courtney B.

"Spotless floors, sanitizer everywhere, and masks required. Felt very safe."

Mark J.

"Easy parking, wheelchair-friendly, and a coffee bar in the waiting area."

Aisha B.

"Modern, clean, and calming—especially the infusion center with mountain views."

David M.

"The MA Jess noticed I was anxious and brought me a weighted blanket. Above and beyond!"

Rachel L.

"Billing is transparent—no surprise charges like at my last neuro."

Daniel R.

"ANC’s telehealth option saved me a 2-hour drive. Seamless tech setup!"

Sophia K.

"The only neurology clinic I’ve been to where you don’t feel like just a number."

Linda H.

"ANC runs like a well-oiled machine. Appointments start on time, and the staff remembers me every visit."

Robert P.

“Amazing. I have been with other Doctors at this practice as well but I had an amazing experience with Dr. Lackey specifically. Very attentive and friendly to work with! Highly recommend!”

Payton E.

"No-nonsense - Wish visits were longer, but his neuropathy staging system helped us prioritize treatments."

Carlos J.

"Migraine magician - Botox + Nurtec combo cut my headache days from 25/month to 4. His headache diary app makes tracking effortless."

Priya N.

“Dr. Dasari has been a God-send for my MS. He is incredibly knowledgeable and makes me feel heard. He allocates his time for me as a patient and I know I couldn’t manage this disease without him!”

Courtney P.

"Brutally honest - Wish she'd sugarcoat less, but her MG treatment plan stopped my hospitalizations. Clinical trials access is a plus."

Patient

"MG crisis hero - Got me into the hospital for IVIG within 4 hours during a bulbar crisis. Her fellow (Dr. Patel) even checked on me at midnight."

Diane K.

"ALS guardian - Coordinates with my pulmonologist, PT, and speech therapist in one shared portal. Her ALS Functional Rating Scale checks keep us proactive."

Thomas W.

“Dr. Yang is nothing but amazing! She has helped me so much with a diagnosis that moved my world upside down. She treats my almost daily migraines as well. She and her team will do what they can to get me the medication I need! She is very compassionate and kind!”

Courtney B.

"Spotless floors, sanitizer everywhere, and masks required. Felt very safe."

Mark J.

"Easy parking, wheelchair-friendly, and a coffee bar in the waiting area."

Aisha B.

"Modern, clean, and calming—especially the infusion center with mountain views."

David M.

"The MA Jess noticed I was anxious and brought me a weighted blanket. Above and beyond!"

Rachel L.

"Billing is transparent—no surprise charges like at my last neuro."

Daniel R.

"ANC’s telehealth option saved me a 2-hour drive. Seamless tech setup!"

Sophia K.

"The only neurology clinic I’ve been to where you don’t feel like just a number."

Linda H.

"ANC runs like a well-oiled machine. Appointments start on time, and the staff remembers me every visit."

Robert P.

“Amazing. I have been with other Doctors at this practice as well but I had an amazing experience with Dr. Lackey specifically. Very attentive and friendly to work with! Highly recommend!”

Payton E.

"No-nonsense - Wish visits were longer, but his neuropathy staging system helped us prioritize treatments."

Carlos J.

"Migraine magician - Botox + Nurtec combo cut my headache days from 25/month to 4. His headache diary app makes tracking effortless."

Priya N.

“Dr. Dasari has been a God-send for my MS. He is incredibly knowledgeable and makes me feel heard. He allocates his time for me as a patient and I know I couldn’t manage this disease without him!”

Courtney P.

"Brutally honest - Wish she'd sugarcoat less, but her MG treatment plan stopped my hospitalizations. Clinical trials access is a plus."

Patient

"MG crisis hero - Got me into the hospital for IVIG within 4 hours during a bulbar crisis. Her fellow (Dr. Patel) even checked on me at midnight."

Diane K.

"ALS guardian - Coordinates with my pulmonologist, PT, and speech therapist in one shared portal. Her ALS Functional Rating Scale checks keep us proactive."

Thomas W.

“Dr. Yang is nothing but amazing! She has helped me so much with a diagnosis that moved my world upside down. She treats my almost daily migraines as well. She and her team will do what they can to get me the medication I need! She is very compassionate and kind!”

Courtney B.

"Spotless floors, sanitizer everywhere, and masks required. Felt very safe."

Mark J.

"Easy parking, wheelchair-friendly, and a coffee bar in the waiting area."

Aisha B.

"Modern, clean, and calming—especially the infusion center with mountain views."

David M.

"The MA Jess noticed I was anxious and brought me a weighted blanket. Above and beyond!"

Rachel L.

"Billing is transparent—no surprise charges like at my last neuro."

Daniel R.

"ANC’s telehealth option saved me a 2-hour drive. Seamless tech setup!"

Sophia K.

"The only neurology clinic I’ve been to where you don’t feel like just a number."

Linda H.

"ANC runs like a well-oiled machine. Appointments start on time, and the staff remembers me every visit."

Robert P.