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Ocrevus® (ocrelizumab) is a monoclonal antibody therapy designed to treat both relapsing forms of multiple sclerosis (RMS) and primary progressive multiple sclerosis (PPMS) in adults. It's part of the anti-CD20 therapy class, which targets and removes specific B cells — immune cells known to contribute to the nerve damage associated with MS.
What sets Ocrevus apart from many other MS treatments is its ability to address both relapsing and progressive forms of the disease, making it one of the most comprehensive treatment options available. In fact, Ocrevus is the first FDA-approved therapy for primary progressive MS, offering hope to patients who previously had limited treatment options.
Ocrevus infusion is administered intravenously at our specialized infusion center. The initial treatment involves:
Premedications (corticosteroid and antihistamine) are given before each infusion to reduce the risk of reactions. Patients are monitored for at least one hour after each infusion. For those who tolerate the treatment well, a shorter infusion option may be available for maintenance doses.
In MS, the immune system attacks the myelin sheath — the insulating layer around nerves in the brain and spinal cord that allows efficient communication between nerve cells. Damage to this sheath can disrupt nerve signals, leading to symptoms such as muscle weakness, coordination difficulties, visual disturbances, and cognitive changes.
Ocrevus works by targeting a specific type of immune cell involved in this process:
What makes Ocrevus unique is its proven effectiveness in treating both relapsing and primary progressive forms of multiple sclerosis. For relapsing MS, it significantly reduces the frequency of relapses and slows disability progression. For primary progressive MS, where symptoms steadily worsen over time, Ocrevus is the first and only treatment shown to slow the progression of physical disability.
While Ocrevus does not cure MS, it helps reduce inflammation, slow disability progression, and minimize new disease activity — supporting improved stability and quality of life. Patients can begin to see measurable effects from Ocrevus in as little as 12 weeks, with benefits continuing to increase over many months to a few years. Clinical trials have demonstrated sustained benefits over extended treatment periods, helping patients maintain function and reduce disease activity long-term.
Like all medications, Ocrevus can cause side effects. Common Ocrevus infusion side effects include:
Less common but serious side effects require immediate medical attention:
Rare but serious complications can include blood clots, heart failure, and stroke. Your healthcare team at our Fort Collins infusion center will monitor you closely during and after each Ocrevus IV infusion to ensure your safety.
The Ocrevus infusion cost depends on individual insurance coverage and benefits. At Advanced Neurology Colorado, our team works to make treatment as seamless and affordable as possible for every patient.
We collaborate with most major commercial insurance providers throughout Colorado — including Aetna, Anthem, Blue Cross Blue Shield, Cigna, Humana, and UnitedHealthcare — as well as Medicaid and Medicare. Our team works closely with your insurance company to maximize your coverage for Ocrevus treatment.
Our infusion staff provides comprehensive support to make treatment more accessible:
Our Colorado infusion center is staffed by board-certified neurologists and BSN-prepared Registered Nurses with extensive experience in neurological infusion care. Patients can expect expert oversight and compassionate, individualized support throughout treatment.
Our medical team brings specialized expertise in multiple sclerosis and complex neurological conditions. With advanced training and years of experience managing MS patients on anti-CD20 therapies, our team of healthcare providers understand the unique considerations for both relapsing and progressive MS treatment.
Our clinical expertise extends beyond MS to include comprehensive care for myasthenia gravis, neuropathy, and other neurological disorders. We have advanced diagnostic capabilities, including electromyography, to provide complete neurological care in one convenient location.
We handle prior authorizations, verify benefits, and assist patients with copay and foundation support programs to reduce financial strain.
Studies, including one from Cigna, show that patients treated in physician-owned infusion centers — such as Advanced Neurology Colorado’s Infusion Center — often pay less overall and out of pocket compared to hospital outpatient centers.
With over 20 years of service to the Colorado community, Advanced Neurology Colorado has built a reputation for excellence in the treatment of MS and other neurological disorders. Our decades of experience mean we've treated thousands of patients with both relapsing and progressive MS, giving us deep insight into the challenges you face and the most effective treatment approaches.
Our established track record with Ocrevus infusion for multiple sclerosis and other anti-CD20 therapies means you benefit from a team that understands not just the science behind the treatment, but the real-world impact on patients' lives. Our team's experience, care, and dedication continue to make a meaningful difference for patients every day.
Multiple Sclerosis
Primary Progressive Multiple Sclerosis
Ocrevus® (ocrelizumab): Approved on March 28, 2017
Genentech (a subsidiary of Roche)
Dr. Lackey was very knowledgeable & easy to talk to. He reviewed my brain & spinal cord MRI’s with me. Since I have so much balance issues, he ordered PT. He also ordered a brain MRI in a year. Very pleased with his care!
"Billing is transparent—no surprise charges like at my last neuro."
Dr. Lackey was great to work with and very knowledgeable. He did more physical tests than any one else has. Very comfortable with him. Mr daughter-in-law, an RN, was there too and very impressed with him.
Dr. Lackey was so understanding and made me feel so safe ! I also appreciate his assistant Amber who is so considerate and efficient! So thankful to have my post stroke care in their hands.❣️
I have only visited Dr Lackey twice, however I feel totally comfortable with him. I was a little worried after being a regular patient of Dr Miller for years, but I feel very safe with him and his knowledge of MS. He is very thorough and personable and I look forward my next visit.
“Dr. Dasari has been a God-send for my MS. He is incredibly knowledgeable and makes me feel heard. He allocates his time for me as a patient and I know I couldn’t manage this disease without him!”
I saw Dr. Lackey for first time. He is a wonderful Dr., very knowledgeable, sincere, listens very well, gave me time to tell him my concerns. Very easy to talk to. He was honest and forthright in his advice and opinion according to my care plan. Thank you Dr Lackey. And welcome to Colorado.
"Spotless floors, sanitizer everywhere, and masks required. Felt very safe."
"I feel confident knowing I'm in capable hands and truly appreciate the thoughtful, attentive care Dr. Dasari provides. I highly recommend him to anyone seeking comprehensive and compassionate neurological care."
Dr. Elijah Lackey is an excellent neurologist and I was lucky enough to land as his patient after 2 almost back to back concussions. I'm grateful to have graduated neurology for the time being after a couple of visits. His friendly demeanor and knowledge calmed my worries and I certainly will not look elsewhere should I need further specialized neurological care.
"Migraine magician - Botox + Nurtec combo cut my headache days from 25/month to 4. His headache diary app makes tracking effortless."
I felt heard with Dr. Lackey and appreciated how thorough he was in both explaining and showing me related details in my MRI. He answered all questions and made sure I knew the plan and next steps. Very grateful I was able to get in knowing wait times are long in NoCo in general for neuro. Thank you!
Dr. Lackey was excellent. He listed to us and offered valuable insights into the condition we are facing. In addition, he made a suggestion regarding meds and possible side-effects that have been noticed. I would highly recommend him.
"The only neurology clinic I’ve been to where you don’t feel like just a number."
"ANC’s telehealth option saved me a 2-hour drive. Seamless tech setup!"
"Brutally honest - Wish she'd sugarcoat less, but her MG treatment plan stopped my hospitalizations. Clinical trials access is a plus."
“Amazing. I have been with other Doctors at this practice as well but I had an amazing experience with Dr. Lackey specifically. Very attentive and friendly to work with! Highly recommend!”
This was our first appointment with Dr Lackey. Professional and caring attitude. Spent time with us to answer all questions and discussed CT and MRI results and follow up care.
Doctor Lackey took time out of his lunch to visit with us when we had to come back in because we had some questions. He is very personable, very helpful, has a great bedside manner, and seems genuinely concerned about his patients.
"No-nonsense. Dr. Dasari's neuropathy staging system helped us prioritize treatments."
Dr. Lackey is fantastic! Takes his time to really listen to your concerns and address them promptly, you can tell he really cares about his patients.
"ANC runs like a well-oiled machine. Appointments start on time, and the staff remembers me every visit."
Dr. Lackey is an outstanding neurologist with compassion, a great depth of knowledge, superb credentials, and exemplary communication skills. He patiently answered my questions and my wife's questions. I highly recommend Dr. Lackey.
Dr Lackey was very personable and listened to all my concerns. He had read my file thoroughly and was up to speed with all my tests. He was happy & kind as well! A pleasure to have as a doctor!
First time meeting with Dr. Lackey and I feel very confident my medical future is in great hands with my MS diagnosis. He seems very knowledgeable and professional with the information he shares. Looking forward to working with him!
"ALS guardian - Coordinates with my pulmonologist, PT, and speech therapist in one shared portal. Her ALS Functional Rating Scale checks keep us proactive."
Dr. Lackey was professional, warm and friendly. He was newly assigned to me. I met him for the first time after one prior phone call. He was familiar with my medical history. Dr. Lackey worked with me rather than just tell me what to do, and listened to my concerns. I found him to be knowledgeable and competent.
"The MA Jess noticed I was anxious and brought me a weighted blanket. Above and beyond!"
"MG crisis hero - Got me into the hospital for IVIG within 4 hours during a bulbar crisis. Her fellow even checked on me at midnight."
“Dr. Yang is nothing but amazing! She has helped me so much with a diagnosis that moved my world upside down. She treats my almost daily migraines as well. She and her team will do what they can to get me the medication I need! She is very compassionate and kind!”
Dr. Lackey is the best. He takes time with me to explain everything and makes sure that my questions are answered. He’s a great listener and I feel very cared for by Dr. Lakey.
"Courtney Weir is an amazing medical professional! She is thorough and addresses all my questions. Each visit she remembers not only me, but asks about my family - above and beyond client care. I love having her, best provider by far! Can't recommend her enough."
Dr. Lackey is fantastic! Takes his time to really listen to your concerns and address them promptly, you can tell he really cares about his patients.
Dr. Lackey was professional, warm and friendly. He was newly assigned to me. I met him for the first time after one prior phone call. He was familiar with my medical history. Dr. Lackey worked with me rather than just tell me what to do, and listened to my concerns. I found him to be knowledgeable and competent.
Dr. Lackey was very knowledgeable & easy to talk to. He reviewed my brain & spinal cord MRI’s with me. Since I have so much balance issues, he ordered PT. He also ordered a brain MRI in a year. Very pleased with his care!
Doctor Lackey took time out of his lunch to visit with us when we had to come back in because we had some questions. He is very personable, very helpful, has a great bedside manner, and seems genuinely concerned about his patients.
Dr. Lackey is an outstanding neurologist with compassion, a great depth of knowledge, superb credentials, and exemplary communication skills. He patiently answered my questions and my wife's questions. I highly recommend Dr. Lackey.
I have only visited Dr Lackey twice, however I feel totally comfortable with him. I was a little worried after being a regular patient of Dr Miller for years, but I feel very safe with him and his knowledge of MS. He is very thorough and personable and I look forward my next visit.
Dr. Lackey is the best. He takes time with me to explain everything and makes sure that my questions are answered. He’s a great listener and I feel very cared for by Dr. Lakey.
Dr. Lackey was excellent. He listed to us and offered valuable insights into the condition we are facing. In addition, he made a suggestion regarding meds and possible side-effects that have been noticed. I would highly recommend him.
First time meeting with Dr. Lackey and I feel very confident my medical future is in great hands with my MS diagnosis. He seems very knowledgeable and professional with the information he shares. Looking forward to working with him!
This was our first appointment with Dr Lackey. Professional and caring attitude. Spent time with us to answer all questions and discussed CT and MRI results and follow up care.
Dr. Elijah Lackey is an excellent neurologist and I was lucky enough to land as his patient after 2 almost back to back concussions. I'm grateful to have graduated neurology for the time being after a couple of visits. His friendly demeanor and knowledge calmed my worries and I certainly will not look elsewhere should I need further specialized neurological care.
Dr Lackey was very personable and listened to all my concerns. He had read my file thoroughly and was up to speed with all my tests. He was happy & kind as well! A pleasure to have as a doctor!
Dr. Lackey was so understanding and made me feel so safe ! I also appreciate his assistant Amber who is so considerate and efficient! So thankful to have my post stroke care in their hands.❣️
Dr. Lackey was great to work with and very knowledgeable. He did more physical tests than any one else has. Very comfortable with him. Mr daughter-in-law, an RN, was there too and very impressed with him.
I saw Dr. Lackey for first time. He is a wonderful Dr., very knowledgeable, sincere, listens very well, gave me time to tell him my concerns. Very easy to talk to. He was honest and forthright in his advice and opinion according to my care plan. Thank you Dr Lackey. And welcome to Colorado.
I felt heard with Dr. Lackey and appreciated how thorough he was in both explaining and showing me related details in my MRI. He answered all questions and made sure I knew the plan and next steps. Very grateful I was able to get in knowing wait times are long in NoCo in general for neuro. Thank you!
“Amazing. I have been with other Doctors at this practice as well but I had an amazing experience with Dr. Lackey specifically. Very attentive and friendly to work with! Highly recommend!”
"No-nonsense. Dr. Dasari's neuropathy staging system helped us prioritize treatments."
"Migraine magician - Botox + Nurtec combo cut my headache days from 25/month to 4. His headache diary app makes tracking effortless."
“Dr. Dasari has been a God-send for my MS. He is incredibly knowledgeable and makes me feel heard. He allocates his time for me as a patient and I know I couldn’t manage this disease without him!”
"Brutally honest - Wish she'd sugarcoat less, but her MG treatment plan stopped my hospitalizations. Clinical trials access is a plus."
"MG crisis hero - Got me into the hospital for IVIG within 4 hours during a bulbar crisis. Her fellow even checked on me at midnight."
"ALS guardian - Coordinates with my pulmonologist, PT, and speech therapist in one shared portal. Her ALS Functional Rating Scale checks keep us proactive."
“Dr. Yang is nothing but amazing! She has helped me so much with a diagnosis that moved my world upside down. She treats my almost daily migraines as well. She and her team will do what they can to get me the medication I need! She is very compassionate and kind!”
"Spotless floors, sanitizer everywhere, and masks required. Felt very safe."
"Courtney Weir is an amazing medical professional! She is thorough and addresses all my questions. Each visit she remembers not only me, but asks about my family - above and beyond client care. I love having her, best provider by far! Can't recommend her enough."
"I feel confident knowing I'm in capable hands and truly appreciate the thoughtful, attentive care Dr. Dasari provides. I highly recommend him to anyone seeking comprehensive and compassionate neurological care."
"The MA Jess noticed I was anxious and brought me a weighted blanket. Above and beyond!"
"Billing is transparent—no surprise charges like at my last neuro."
"ANC’s telehealth option saved me a 2-hour drive. Seamless tech setup!"
"The only neurology clinic I’ve been to where you don’t feel like just a number."
"ANC runs like a well-oiled machine. Appointments start on time, and the staff remembers me every visit."
Dr. Lackey is fantastic! Takes his time to really listen to your concerns and address them promptly, you can tell he really cares about his patients.
Dr. Lackey was professional, warm and friendly. He was newly assigned to me. I met him for the first time after one prior phone call. He was familiar with my medical history. Dr. Lackey worked with me rather than just tell me what to do, and listened to my concerns. I found him to be knowledgeable and competent.
Dr. Lackey was very knowledgeable & easy to talk to. He reviewed my brain & spinal cord MRI’s with me. Since I have so much balance issues, he ordered PT. He also ordered a brain MRI in a year. Very pleased with his care!
Doctor Lackey took time out of his lunch to visit with us when we had to come back in because we had some questions. He is very personable, very helpful, has a great bedside manner, and seems genuinely concerned about his patients.
Dr. Lackey is an outstanding neurologist with compassion, a great depth of knowledge, superb credentials, and exemplary communication skills. He patiently answered my questions and my wife's questions. I highly recommend Dr. Lackey.
I have only visited Dr Lackey twice, however I feel totally comfortable with him. I was a little worried after being a regular patient of Dr Miller for years, but I feel very safe with him and his knowledge of MS. He is very thorough and personable and I look forward my next visit.
Dr. Lackey is the best. He takes time with me to explain everything and makes sure that my questions are answered. He’s a great listener and I feel very cared for by Dr. Lakey.
Dr. Lackey was excellent. He listed to us and offered valuable insights into the condition we are facing. In addition, he made a suggestion regarding meds and possible side-effects that have been noticed. I would highly recommend him.
First time meeting with Dr. Lackey and I feel very confident my medical future is in great hands with my MS diagnosis. He seems very knowledgeable and professional with the information he shares. Looking forward to working with him!
This was our first appointment with Dr Lackey. Professional and caring attitude. Spent time with us to answer all questions and discussed CT and MRI results and follow up care.
Dr. Elijah Lackey is an excellent neurologist and I was lucky enough to land as his patient after 2 almost back to back concussions. I'm grateful to have graduated neurology for the time being after a couple of visits. His friendly demeanor and knowledge calmed my worries and I certainly will not look elsewhere should I need further specialized neurological care.
Dr Lackey was very personable and listened to all my concerns. He had read my file thoroughly and was up to speed with all my tests. He was happy & kind as well! A pleasure to have as a doctor!
Dr. Lackey was so understanding and made me feel so safe ! I also appreciate his assistant Amber who is so considerate and efficient! So thankful to have my post stroke care in their hands.❣️
Dr. Lackey was great to work with and very knowledgeable. He did more physical tests than any one else has. Very comfortable with him. Mr daughter-in-law, an RN, was there too and very impressed with him.
I saw Dr. Lackey for first time. He is a wonderful Dr., very knowledgeable, sincere, listens very well, gave me time to tell him my concerns. Very easy to talk to. He was honest and forthright in his advice and opinion according to my care plan. Thank you Dr Lackey. And welcome to Colorado.
I felt heard with Dr. Lackey and appreciated how thorough he was in both explaining and showing me related details in my MRI. He answered all questions and made sure I knew the plan and next steps. Very grateful I was able to get in knowing wait times are long in NoCo in general for neuro. Thank you!
“Amazing. I have been with other Doctors at this practice as well but I had an amazing experience with Dr. Lackey specifically. Very attentive and friendly to work with! Highly recommend!”
"No-nonsense. Dr. Dasari's neuropathy staging system helped us prioritize treatments."
"Migraine magician - Botox + Nurtec combo cut my headache days from 25/month to 4. His headache diary app makes tracking effortless."
“Dr. Dasari has been a God-send for my MS. He is incredibly knowledgeable and makes me feel heard. He allocates his time for me as a patient and I know I couldn’t manage this disease without him!”
"Brutally honest - Wish she'd sugarcoat less, but her MG treatment plan stopped my hospitalizations. Clinical trials access is a plus."
"MG crisis hero - Got me into the hospital for IVIG within 4 hours during a bulbar crisis. Her fellow even checked on me at midnight."
"ALS guardian - Coordinates with my pulmonologist, PT, and speech therapist in one shared portal. Her ALS Functional Rating Scale checks keep us proactive."
“Dr. Yang is nothing but amazing! She has helped me so much with a diagnosis that moved my world upside down. She treats my almost daily migraines as well. She and her team will do what they can to get me the medication I need! She is very compassionate and kind!”
"Spotless floors, sanitizer everywhere, and masks required. Felt very safe."
"Courtney Weir is an amazing medical professional! She is thorough and addresses all my questions. Each visit she remembers not only me, but asks about my family - above and beyond client care. I love having her, best provider by far! Can't recommend her enough."
"I feel confident knowing I'm in capable hands and truly appreciate the thoughtful, attentive care Dr. Dasari provides. I highly recommend him to anyone seeking comprehensive and compassionate neurological care."
"The MA Jess noticed I was anxious and brought me a weighted blanket. Above and beyond!"
"Billing is transparent—no surprise charges like at my last neuro."
"ANC’s telehealth option saved me a 2-hour drive. Seamless tech setup!"
"The only neurology clinic I’ve been to where you don’t feel like just a number."
"ANC runs like a well-oiled machine. Appointments start on time, and the staff remembers me every visit."
Dr. Lackey is fantastic! Takes his time to really listen to your concerns and address them promptly, you can tell he really cares about his patients.
Dr. Lackey was professional, warm and friendly. He was newly assigned to me. I met him for the first time after one prior phone call. He was familiar with my medical history. Dr. Lackey worked with me rather than just tell me what to do, and listened to my concerns. I found him to be knowledgeable and competent.
Dr. Lackey was very knowledgeable & easy to talk to. He reviewed my brain & spinal cord MRI’s with me. Since I have so much balance issues, he ordered PT. He also ordered a brain MRI in a year. Very pleased with his care!
Doctor Lackey took time out of his lunch to visit with us when we had to come back in because we had some questions. He is very personable, very helpful, has a great bedside manner, and seems genuinely concerned about his patients.
Dr. Lackey is an outstanding neurologist with compassion, a great depth of knowledge, superb credentials, and exemplary communication skills. He patiently answered my questions and my wife's questions. I highly recommend Dr. Lackey.
I have only visited Dr Lackey twice, however I feel totally comfortable with him. I was a little worried after being a regular patient of Dr Miller for years, but I feel very safe with him and his knowledge of MS. He is very thorough and personable and I look forward my next visit.
Dr. Lackey is the best. He takes time with me to explain everything and makes sure that my questions are answered. He’s a great listener and I feel very cared for by Dr. Lakey.
Dr. Lackey was excellent. He listed to us and offered valuable insights into the condition we are facing. In addition, he made a suggestion regarding meds and possible side-effects that have been noticed. I would highly recommend him.
First time meeting with Dr. Lackey and I feel very confident my medical future is in great hands with my MS diagnosis. He seems very knowledgeable and professional with the information he shares. Looking forward to working with him!
This was our first appointment with Dr Lackey. Professional and caring attitude. Spent time with us to answer all questions and discussed CT and MRI results and follow up care.
Dr. Elijah Lackey is an excellent neurologist and I was lucky enough to land as his patient after 2 almost back to back concussions. I'm grateful to have graduated neurology for the time being after a couple of visits. His friendly demeanor and knowledge calmed my worries and I certainly will not look elsewhere should I need further specialized neurological care.
Dr Lackey was very personable and listened to all my concerns. He had read my file thoroughly and was up to speed with all my tests. He was happy & kind as well! A pleasure to have as a doctor!
Dr. Lackey was so understanding and made me feel so safe ! I also appreciate his assistant Amber who is so considerate and efficient! So thankful to have my post stroke care in their hands.❣️
Dr. Lackey was great to work with and very knowledgeable. He did more physical tests than any one else has. Very comfortable with him. Mr daughter-in-law, an RN, was there too and very impressed with him.
I saw Dr. Lackey for first time. He is a wonderful Dr., very knowledgeable, sincere, listens very well, gave me time to tell him my concerns. Very easy to talk to. He was honest and forthright in his advice and opinion according to my care plan. Thank you Dr Lackey. And welcome to Colorado.
I felt heard with Dr. Lackey and appreciated how thorough he was in both explaining and showing me related details in my MRI. He answered all questions and made sure I knew the plan and next steps. Very grateful I was able to get in knowing wait times are long in NoCo in general for neuro. Thank you!
“Amazing. I have been with other Doctors at this practice as well but I had an amazing experience with Dr. Lackey specifically. Very attentive and friendly to work with! Highly recommend!”
"No-nonsense. Dr. Dasari's neuropathy staging system helped us prioritize treatments."
"Migraine magician - Botox + Nurtec combo cut my headache days from 25/month to 4. His headache diary app makes tracking effortless."
“Dr. Dasari has been a God-send for my MS. He is incredibly knowledgeable and makes me feel heard. He allocates his time for me as a patient and I know I couldn’t manage this disease without him!”
"Brutally honest - Wish she'd sugarcoat less, but her MG treatment plan stopped my hospitalizations. Clinical trials access is a plus."
"MG crisis hero - Got me into the hospital for IVIG within 4 hours during a bulbar crisis. Her fellow even checked on me at midnight."
"ALS guardian - Coordinates with my pulmonologist, PT, and speech therapist in one shared portal. Her ALS Functional Rating Scale checks keep us proactive."
“Dr. Yang is nothing but amazing! She has helped me so much with a diagnosis that moved my world upside down. She treats my almost daily migraines as well. She and her team will do what they can to get me the medication I need! She is very compassionate and kind!”
"Spotless floors, sanitizer everywhere, and masks required. Felt very safe."
"Courtney Weir is an amazing medical professional! She is thorough and addresses all my questions. Each visit she remembers not only me, but asks about my family - above and beyond client care. I love having her, best provider by far! Can't recommend her enough."
"I feel confident knowing I'm in capable hands and truly appreciate the thoughtful, attentive care Dr. Dasari provides. I highly recommend him to anyone seeking comprehensive and compassionate neurological care."
"The MA Jess noticed I was anxious and brought me a weighted blanket. Above and beyond!"
"Billing is transparent—no surprise charges like at my last neuro."
"ANC’s telehealth option saved me a 2-hour drive. Seamless tech setup!"
"The only neurology clinic I’ve been to where you don’t feel like just a number."
"ANC runs like a well-oiled machine. Appointments start on time, and the staff remembers me every visit."
