Vyvgart

What is Vyvgart®?

Vyvgart® (efgartigimod alfa-fcab) treats generalized myasthenia gravis, often shortened to gMG, in adults who test positive for AChR antibodies. Your doctor can tell you whether you are from a blood test.

In myasthenia gravis, your muscles get weak and tire out quickly. It can affect walking, lifting things, speaking, swallowing, and moving your eyes. Symptoms often get worse the more you use a muscle and better when you rest.

Vyvgart is given in rounds, not on an endless schedule. One round is 4 weekly treatments. Then you take a break.

Here is what a round looks like:

  • Your dose: Based on your weight
  • How often: Once a week for 4 weeks, then a break
  • Total appointment time: About 2.5 - 3 hours per visit
  • Your next round: Based on how you are feeling, not on a set calendar date

Everyone's timing is different. Some people need their next round sooner than others. Keeping track of how you feel between rounds is the best way to help your neurologist decide when to start again.

How does Vyvgart work?

Your muscles move when your nerves send them a signal. In myasthenia gravis, your immune system makes proteins called antibodies that block those signals. Your muscles never get the message, so they feel weak and tired.

Your body normally recycles antibodies so they can keep working for a long time. A receptor called FcRn does that recycling job.

The problem is that FcRn recycles the harmful antibodies too. It keeps them in your blood instead of clearing them out.

Here is what it does:

  • Vyvgart blocks FcRn. It stops the recycling process.
  • Harmful antibodies get cleared out. Your body breaks them down instead of keeping them.
  • Nerve signals get through again. Your muscles start receiving the messages they were missing.
  • Strength improves. Many people find daily tasks easier.

Many people notice more strength and energy during their first round, though this varies from person to person.

Vyvgart is not a cure. It manages your symptoms. The benefit usually builds during a round and then fades before the next one, which is a normal part of how it works.

Common side effects:

  • Infections in your nose, throat, or lungs
  • Headache
  • Bladder infections
  • Soreness where your IV goes in

Serious side effects — get medical help right away:

  • Infections. Vyvgart lowers your antibody levels, so infections may be harder to fight off. If you are sick, your treatment will be put off until you are better.
  • Reactions during treatment. These can include a rash, swelling of the face, lips, or throat, or trouble breathing.
  • Live vaccines. You should not get live vaccines while on Vyvgart. Talk with your care team about your shots before you start.

Send a Referral

This provider is not available to book online. Give us a call or fill out a form and someone from our team will reach out to you.

Therapy:
Vyvgart
Referral Form:
Click Here
What It Treats:

Generalized myasthenia gravis (AChR antibody positive), adults

FDA Approval:

Generalized myasthenia gravis: approved December 17, 2021

Manufacturer:

argenx SE

Route:
Intravenous (IV) infusion

Why Patients Choose Advanced Neurology of Colorado's Infusion Center to Receive Their Vyvgart®‍ Infusion:

Learn more about Infusion Center at ANC

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What Our Patients Have to Say

Dr. Lackey is the best. He takes time with me to explain everything and makes sure that my questions are answered. He’s a great listener and I feel very cared for by Dr. Lakey.

Denice C.

"The only neurology clinic I’ve been to where you don’t feel like just a number."

Linda H.

“Dr. Dasari has been a God-send for my MS. He is incredibly knowledgeable and makes me feel heard. He allocates his time for me as a patient and I know I couldn’t manage this disease without him!”

Courtney P.

"Love Dr. Gilder, have been with her close to 20 years. I have MS and Migraine. 2 diseases, similar treatments. Most of the time, MS is much easier to manage. Thanks to Dr. Gilder and staff, we keep on fighting."

Andrea M.

Dr. Lackey is fantastic! Takes his time to really listen to your concerns and address them promptly, you can tell he really cares about his patients.

Andrea V.

Dr. Elijah Lackey is an excellent neurologist and I was lucky enough to land as his patient after 2 almost back to back concussions. I'm grateful to have graduated neurology for the time being after a couple of visits. His friendly demeanor and knowledge calmed my worries and I certainly will not look elsewhere should I need further specialized neurological care.

Tara R.

First time meeting with Dr. Lackey and I feel very confident my medical future is in great hands with my MS diagnosis. He seems very knowledgeable and professional with the information he shares. Looking forward to working with him!

Stefen W.

"Migraine magician - Botox + Nurtec combo cut my headache days from 25/month to 4. His headache diary app makes tracking effortless."

Priya N.

"I feel confident knowing I'm in capable hands and truly appreciate the thoughtful, attentive care Dr. Dasari provides. I highly recommend him to anyone seeking comprehensive and compassionate neurological care."

Heather L.

Dr. Lackey was professional, warm and friendly. He was newly assigned to me. I met him for the first time after one prior phone call. He was familiar with my medical history. Dr. Lackey worked with me rather than just tell me what to do, and listened to my concerns. I found him to be knowledgeable and competent.

Maureen R.

I have only visited Dr Lackey twice, however I feel totally comfortable with him. I was a little worried after being a regular patient of Dr Miller for years, but I feel very safe with him and his knowledge of MS. He is very thorough and personable and I look forward my next visit.

Toni B.

This was our first appointment with Dr Lackey. Professional and caring attitude. Spent time with us to answer all questions and discussed CT and MRI results and follow up care.

Hallie

Dr. Lackey was excellent. He listed to us and offered valuable insights into the condition we are facing. In addition, he made a suggestion regarding meds and possible side-effects that have been noticed. I would highly recommend him.

Regis S.

"Billing is transparent—no surprise charges like at my last neuro."

Daniel R.

Dr Lackey was very personable and listened to all my concerns. He had read my file thoroughly and was up to speed with all my tests. He was happy & kind as well! A pleasure to have as a doctor!

SPS Office

Dr. Lackey was so understanding and made me feel so safe ! I also appreciate his assistant Amber who is so considerate and efficient! So thankful to have my post stroke care in their hands.❣️

Kathy M.

Dr. Lackey is an outstanding neurologist with compassion, a great depth of knowledge, superb credentials, and exemplary communication skills. He patiently answered my questions and my wife's questions. I highly recommend Dr. Lackey.

Robert M.

"ANC runs like a well-oiled machine. Appointments start on time, and the staff remembers me every visit."

Robert P.

"Spotless floors, sanitizer everywhere, and masks required. Felt very safe."

Mark J.

Dr. Lackey was great to work with and very knowledgeable. He did more physical tests than any one else has. Very comfortable with him. Mr daughter-in-law, an RN, was there too and very impressed with him.

Karen R.

I felt heard with Dr. Lackey and appreciated how thorough he was in both explaining and showing me related details in my MRI. He answered all questions and made sure I knew the plan and next steps. Very grateful I was able to get in knowing wait times are long in NoCo in general for neuro. Thank you!

Marcey S.

"ANC’s telehealth option saved me a 2-hour drive. Seamless tech setup!"

Sophia K.

"Dr. Gilder has been my neurologist for going on 10 years now. She is incredibly knowledgeable in choosing a treatment plan that will work best. Most importantly, she listens and won't BS you when it comes to concerns she may have. All in all, you're in good hands by selecting Dr. Beverly Gilder as your specialist."

Steve G.

"The MA Jess noticed I was anxious and brought me a weighted blanket. Above and beyond!"

Rachel L.

Dr. Lackey was very knowledgeable & easy to talk to. He reviewed my brain & spinal cord MRI’s with me. Since I have so much balance issues, he ordered PT. He also ordered a brain MRI in a year. Very pleased with his care!

Kate L.

"Dr. Gilder is awesome! Every time I see her, she always takes the time to visit with me and really understand how I’m doing. She doesn’t make snap decisions but takes her time to make a diagnosis. I highly recommend her."

Brenda P.

I saw Dr. Lackey for first time. He is a wonderful Dr., very knowledgeable, sincere, listens very well, gave me time to tell him my concerns. Very easy to talk to. He was honest and forthright in his advice and opinion according to my care plan. Thank you Dr Lackey. And welcome to Colorado.

Carol T.

Doctor Lackey took time out of his lunch to visit with us when we had to come back in because we had some questions. He is very personable, very helpful, has a great bedside manner, and seems genuinely concerned about his patients.

Betty L.

"No-nonsense. Dr. Dasari's neuropathy staging system helped us prioritize treatments."

Carlos J.

“Amazing. I have been with other Doctors at this practice as well but I had an amazing experience with Dr. Lackey specifically. Very attentive and friendly to work with! Highly recommend!”

Payton E.

"Dr. Gilder has been my neurologist for going on 10 years now. She is incredibly knowledgeable in choosing a treatment plan that will work best. Most importantly, she listens and won't BS you when it comes to concerns she may have. All in all, you're in good hands by selecting Dr. Beverly Gilder as your specialist."

Steve G.

"Love Dr. Gilder, have been with her close to 20 years. I have MS and Migraine. 2 diseases, similar treatments. Most of the time, MS is much easier to manage. Thanks to Dr. Gilder and staff, we keep on fighting."

Andrea M.

"Dr. Gilder is awesome! Every time I see her, she always takes the time to visit with me and really understand how I’m doing. She doesn’t make snap decisions but takes her time to make a diagnosis. I highly recommend her."

Brenda P.

Dr. Lackey is fantastic! Takes his time to really listen to your concerns and address them promptly, you can tell he really cares about his patients.

Andrea V.

Dr. Lackey was professional, warm and friendly. He was newly assigned to me. I met him for the first time after one prior phone call. He was familiar with my medical history. Dr. Lackey worked with me rather than just tell me what to do, and listened to my concerns. I found him to be knowledgeable and competent.

Maureen R.

Dr. Lackey was very knowledgeable & easy to talk to. He reviewed my brain & spinal cord MRI’s with me. Since I have so much balance issues, he ordered PT. He also ordered a brain MRI in a year. Very pleased with his care!

Kate L.

Doctor Lackey took time out of his lunch to visit with us when we had to come back in because we had some questions. He is very personable, very helpful, has a great bedside manner, and seems genuinely concerned about his patients.

Betty L.

Dr. Lackey is an outstanding neurologist with compassion, a great depth of knowledge, superb credentials, and exemplary communication skills. He patiently answered my questions and my wife's questions. I highly recommend Dr. Lackey.

Robert M.

I have only visited Dr Lackey twice, however I feel totally comfortable with him. I was a little worried after being a regular patient of Dr Miller for years, but I feel very safe with him and his knowledge of MS. He is very thorough and personable and I look forward my next visit.

Toni B.

Dr. Lackey is the best. He takes time with me to explain everything and makes sure that my questions are answered. He’s a great listener and I feel very cared for by Dr. Lakey.

Denice C.

Dr. Lackey was excellent. He listed to us and offered valuable insights into the condition we are facing. In addition, he made a suggestion regarding meds and possible side-effects that have been noticed. I would highly recommend him.

Regis S.

First time meeting with Dr. Lackey and I feel very confident my medical future is in great hands with my MS diagnosis. He seems very knowledgeable and professional with the information he shares. Looking forward to working with him!

Stefen W.

This was our first appointment with Dr Lackey. Professional and caring attitude. Spent time with us to answer all questions and discussed CT and MRI results and follow up care.

Hallie

Dr. Elijah Lackey is an excellent neurologist and I was lucky enough to land as his patient after 2 almost back to back concussions. I'm grateful to have graduated neurology for the time being after a couple of visits. His friendly demeanor and knowledge calmed my worries and I certainly will not look elsewhere should I need further specialized neurological care.

Tara R.

Dr Lackey was very personable and listened to all my concerns. He had read my file thoroughly and was up to speed with all my tests. He was happy & kind as well! A pleasure to have as a doctor!

SPS Office

Dr. Lackey was so understanding and made me feel so safe ! I also appreciate his assistant Amber who is so considerate and efficient! So thankful to have my post stroke care in their hands.❣️

Kathy M.

Dr. Lackey was great to work with and very knowledgeable. He did more physical tests than any one else has. Very comfortable with him. Mr daughter-in-law, an RN, was there too and very impressed with him.

Karen R.

I saw Dr. Lackey for first time. He is a wonderful Dr., very knowledgeable, sincere, listens very well, gave me time to tell him my concerns. Very easy to talk to. He was honest and forthright in his advice and opinion according to my care plan. Thank you Dr Lackey. And welcome to Colorado.

Carol T.

I felt heard with Dr. Lackey and appreciated how thorough he was in both explaining and showing me related details in my MRI. He answered all questions and made sure I knew the plan and next steps. Very grateful I was able to get in knowing wait times are long in NoCo in general for neuro. Thank you!

Marcey S.

“Amazing. I have been with other Doctors at this practice as well but I had an amazing experience with Dr. Lackey specifically. Very attentive and friendly to work with! Highly recommend!”

Payton E.

"No-nonsense. Dr. Dasari's neuropathy staging system helped us prioritize treatments."

Carlos J.

"Migraine magician - Botox + Nurtec combo cut my headache days from 25/month to 4. His headache diary app makes tracking effortless."

Priya N.

“Dr. Dasari has been a God-send for my MS. He is incredibly knowledgeable and makes me feel heard. He allocates his time for me as a patient and I know I couldn’t manage this disease without him!”

Courtney P.

"Spotless floors, sanitizer everywhere, and masks required. Felt very safe."

Mark J.

"I feel confident knowing I'm in capable hands and truly appreciate the thoughtful, attentive care Dr. Dasari provides. I highly recommend him to anyone seeking comprehensive and compassionate neurological care."

Heather L.

"The MA Jess noticed I was anxious and brought me a weighted blanket. Above and beyond!"

Rachel L.

"Billing is transparent—no surprise charges like at my last neuro."

Daniel R.

"ANC’s telehealth option saved me a 2-hour drive. Seamless tech setup!"

Sophia K.

"The only neurology clinic I’ve been to where you don’t feel like just a number."

Linda H.

"ANC runs like a well-oiled machine. Appointments start on time, and the staff remembers me every visit."

Robert P.

"Dr. Gilder has been my neurologist for going on 10 years now. She is incredibly knowledgeable in choosing a treatment plan that will work best. Most importantly, she listens and won't BS you when it comes to concerns she may have. All in all, you're in good hands by selecting Dr. Beverly Gilder as your specialist."

Steve G.

"Love Dr. Gilder, have been with her close to 20 years. I have MS and Migraine. 2 diseases, similar treatments. Most of the time, MS is much easier to manage. Thanks to Dr. Gilder and staff, we keep on fighting."

Andrea M.

"Dr. Gilder is awesome! Every time I see her, she always takes the time to visit with me and really understand how I’m doing. She doesn’t make snap decisions but takes her time to make a diagnosis. I highly recommend her."

Brenda P.

Dr. Lackey is fantastic! Takes his time to really listen to your concerns and address them promptly, you can tell he really cares about his patients.

Andrea V.

Dr. Lackey was professional, warm and friendly. He was newly assigned to me. I met him for the first time after one prior phone call. He was familiar with my medical history. Dr. Lackey worked with me rather than just tell me what to do, and listened to my concerns. I found him to be knowledgeable and competent.

Maureen R.

Dr. Lackey was very knowledgeable & easy to talk to. He reviewed my brain & spinal cord MRI’s with me. Since I have so much balance issues, he ordered PT. He also ordered a brain MRI in a year. Very pleased with his care!

Kate L.

Doctor Lackey took time out of his lunch to visit with us when we had to come back in because we had some questions. He is very personable, very helpful, has a great bedside manner, and seems genuinely concerned about his patients.

Betty L.

Dr. Lackey is an outstanding neurologist with compassion, a great depth of knowledge, superb credentials, and exemplary communication skills. He patiently answered my questions and my wife's questions. I highly recommend Dr. Lackey.

Robert M.

I have only visited Dr Lackey twice, however I feel totally comfortable with him. I was a little worried after being a regular patient of Dr Miller for years, but I feel very safe with him and his knowledge of MS. He is very thorough and personable and I look forward my next visit.

Toni B.

Dr. Lackey is the best. He takes time with me to explain everything and makes sure that my questions are answered. He’s a great listener and I feel very cared for by Dr. Lakey.

Denice C.

Dr. Lackey was excellent. He listed to us and offered valuable insights into the condition we are facing. In addition, he made a suggestion regarding meds and possible side-effects that have been noticed. I would highly recommend him.

Regis S.

First time meeting with Dr. Lackey and I feel very confident my medical future is in great hands with my MS diagnosis. He seems very knowledgeable and professional with the information he shares. Looking forward to working with him!

Stefen W.

This was our first appointment with Dr Lackey. Professional and caring attitude. Spent time with us to answer all questions and discussed CT and MRI results and follow up care.

Hallie

Dr. Elijah Lackey is an excellent neurologist and I was lucky enough to land as his patient after 2 almost back to back concussions. I'm grateful to have graduated neurology for the time being after a couple of visits. His friendly demeanor and knowledge calmed my worries and I certainly will not look elsewhere should I need further specialized neurological care.

Tara R.

Dr Lackey was very personable and listened to all my concerns. He had read my file thoroughly and was up to speed with all my tests. He was happy & kind as well! A pleasure to have as a doctor!

SPS Office

Dr. Lackey was so understanding and made me feel so safe ! I also appreciate his assistant Amber who is so considerate and efficient! So thankful to have my post stroke care in their hands.❣️

Kathy M.

Dr. Lackey was great to work with and very knowledgeable. He did more physical tests than any one else has. Very comfortable with him. Mr daughter-in-law, an RN, was there too and very impressed with him.

Karen R.

I saw Dr. Lackey for first time. He is a wonderful Dr., very knowledgeable, sincere, listens very well, gave me time to tell him my concerns. Very easy to talk to. He was honest and forthright in his advice and opinion according to my care plan. Thank you Dr Lackey. And welcome to Colorado.

Carol T.

I felt heard with Dr. Lackey and appreciated how thorough he was in both explaining and showing me related details in my MRI. He answered all questions and made sure I knew the plan and next steps. Very grateful I was able to get in knowing wait times are long in NoCo in general for neuro. Thank you!

Marcey S.

“Amazing. I have been with other Doctors at this practice as well but I had an amazing experience with Dr. Lackey specifically. Very attentive and friendly to work with! Highly recommend!”

Payton E.

"No-nonsense. Dr. Dasari's neuropathy staging system helped us prioritize treatments."

Carlos J.

"Migraine magician - Botox + Nurtec combo cut my headache days from 25/month to 4. His headache diary app makes tracking effortless."

Priya N.

“Dr. Dasari has been a God-send for my MS. He is incredibly knowledgeable and makes me feel heard. He allocates his time for me as a patient and I know I couldn’t manage this disease without him!”

Courtney P.

"Spotless floors, sanitizer everywhere, and masks required. Felt very safe."

Mark J.

"I feel confident knowing I'm in capable hands and truly appreciate the thoughtful, attentive care Dr. Dasari provides. I highly recommend him to anyone seeking comprehensive and compassionate neurological care."

Heather L.

"The MA Jess noticed I was anxious and brought me a weighted blanket. Above and beyond!"

Rachel L.

"Billing is transparent—no surprise charges like at my last neuro."

Daniel R.

"ANC’s telehealth option saved me a 2-hour drive. Seamless tech setup!"

Sophia K.

"The only neurology clinic I’ve been to where you don’t feel like just a number."

Linda H.

"ANC runs like a well-oiled machine. Appointments start on time, and the staff remembers me every visit."

Robert P.

"Dr. Gilder has been my neurologist for going on 10 years now. She is incredibly knowledgeable in choosing a treatment plan that will work best. Most importantly, she listens and won't BS you when it comes to concerns she may have. All in all, you're in good hands by selecting Dr. Beverly Gilder as your specialist."

Steve G.

"Love Dr. Gilder, have been with her close to 20 years. I have MS and Migraine. 2 diseases, similar treatments. Most of the time, MS is much easier to manage. Thanks to Dr. Gilder and staff, we keep on fighting."

Andrea M.

"Dr. Gilder is awesome! Every time I see her, she always takes the time to visit with me and really understand how I’m doing. She doesn’t make snap decisions but takes her time to make a diagnosis. I highly recommend her."

Brenda P.

Dr. Lackey is fantastic! Takes his time to really listen to your concerns and address them promptly, you can tell he really cares about his patients.

Andrea V.

Dr. Lackey was professional, warm and friendly. He was newly assigned to me. I met him for the first time after one prior phone call. He was familiar with my medical history. Dr. Lackey worked with me rather than just tell me what to do, and listened to my concerns. I found him to be knowledgeable and competent.

Maureen R.

Dr. Lackey was very knowledgeable & easy to talk to. He reviewed my brain & spinal cord MRI’s with me. Since I have so much balance issues, he ordered PT. He also ordered a brain MRI in a year. Very pleased with his care!

Kate L.

Doctor Lackey took time out of his lunch to visit with us when we had to come back in because we had some questions. He is very personable, very helpful, has a great bedside manner, and seems genuinely concerned about his patients.

Betty L.

Dr. Lackey is an outstanding neurologist with compassion, a great depth of knowledge, superb credentials, and exemplary communication skills. He patiently answered my questions and my wife's questions. I highly recommend Dr. Lackey.

Robert M.

I have only visited Dr Lackey twice, however I feel totally comfortable with him. I was a little worried after being a regular patient of Dr Miller for years, but I feel very safe with him and his knowledge of MS. He is very thorough and personable and I look forward my next visit.

Toni B.

Dr. Lackey is the best. He takes time with me to explain everything and makes sure that my questions are answered. He’s a great listener and I feel very cared for by Dr. Lakey.

Denice C.

Dr. Lackey was excellent. He listed to us and offered valuable insights into the condition we are facing. In addition, he made a suggestion regarding meds and possible side-effects that have been noticed. I would highly recommend him.

Regis S.

First time meeting with Dr. Lackey and I feel very confident my medical future is in great hands with my MS diagnosis. He seems very knowledgeable and professional with the information he shares. Looking forward to working with him!

Stefen W.

This was our first appointment with Dr Lackey. Professional and caring attitude. Spent time with us to answer all questions and discussed CT and MRI results and follow up care.

Hallie

Dr. Elijah Lackey is an excellent neurologist and I was lucky enough to land as his patient after 2 almost back to back concussions. I'm grateful to have graduated neurology for the time being after a couple of visits. His friendly demeanor and knowledge calmed my worries and I certainly will not look elsewhere should I need further specialized neurological care.

Tara R.

Dr Lackey was very personable and listened to all my concerns. He had read my file thoroughly and was up to speed with all my tests. He was happy & kind as well! A pleasure to have as a doctor!

SPS Office

Dr. Lackey was so understanding and made me feel so safe ! I also appreciate his assistant Amber who is so considerate and efficient! So thankful to have my post stroke care in their hands.❣️

Kathy M.

Dr. Lackey was great to work with and very knowledgeable. He did more physical tests than any one else has. Very comfortable with him. Mr daughter-in-law, an RN, was there too and very impressed with him.

Karen R.

I saw Dr. Lackey for first time. He is a wonderful Dr., very knowledgeable, sincere, listens very well, gave me time to tell him my concerns. Very easy to talk to. He was honest and forthright in his advice and opinion according to my care plan. Thank you Dr Lackey. And welcome to Colorado.

Carol T.

I felt heard with Dr. Lackey and appreciated how thorough he was in both explaining and showing me related details in my MRI. He answered all questions and made sure I knew the plan and next steps. Very grateful I was able to get in knowing wait times are long in NoCo in general for neuro. Thank you!

Marcey S.

“Amazing. I have been with other Doctors at this practice as well but I had an amazing experience with Dr. Lackey specifically. Very attentive and friendly to work with! Highly recommend!”

Payton E.

"No-nonsense. Dr. Dasari's neuropathy staging system helped us prioritize treatments."

Carlos J.

"Migraine magician - Botox + Nurtec combo cut my headache days from 25/month to 4. His headache diary app makes tracking effortless."

Priya N.

“Dr. Dasari has been a God-send for my MS. He is incredibly knowledgeable and makes me feel heard. He allocates his time for me as a patient and I know I couldn’t manage this disease without him!”

Courtney P.

"Spotless floors, sanitizer everywhere, and masks required. Felt very safe."

Mark J.

"I feel confident knowing I'm in capable hands and truly appreciate the thoughtful, attentive care Dr. Dasari provides. I highly recommend him to anyone seeking comprehensive and compassionate neurological care."

Heather L.

"The MA Jess noticed I was anxious and brought me a weighted blanket. Above and beyond!"

Rachel L.

"Billing is transparent—no surprise charges like at my last neuro."

Daniel R.

"ANC’s telehealth option saved me a 2-hour drive. Seamless tech setup!"

Sophia K.

"The only neurology clinic I’ve been to where you don’t feel like just a number."

Linda H.

"ANC runs like a well-oiled machine. Appointments start on time, and the staff remembers me every visit."

Robert P.