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Rituxan® (rituximab) is a monoclonal antibody treatment used for various autoimmune diseases and certain blood cancers by targeting CD20, a protein found on B-cells. By attaching to CD20, Rituxan® helps remove harmful B-cells, reducing inflammation and the immune system's attack on healthy tissue.
At Advanced Neurology Colorado, we specialize in using Rituxan infusion therapy for neurological conditions including multiple sclerosis, myasthenia gravis, and neuropathy. Rituxan's unique ability to target B-cells makes it particularly effective for autoimmune neurological disorders where B-cells contribute to nerve and muscle damage.
Rituxan IV infusion is administered at our specialized infusion center. The Rituxan infusion protocol typically includes:
The treatment schedule varies based on your specific condition. Common protocols include:
Premedications are typically given before each infusion to minimize the risk of infusion reactions.
In autoimmune neurological conditions, the immune system mistakenly attacks healthy tissue in the nervous system. B-cells—a type of white blood cell—play a central role in this process by producing antibodies that target the body's own nerves, muscles, or myelin (the protective covering around nerves). This leads to inflammation, nerve damage, and the symptoms associated with conditions like multiple sclerosis, myasthenia gravis, and certain forms of neuropathy.
Rituxan works through a specific mechanism:
What makes Rituxan unique is its historical significance as the first monoclonal antibody approved for targeting CD20, and its proven effectiveness across multiple autoimmune conditions. As a chimeric monoclonal antibody, Rituxan specifically destroys B-cells while sparing other important immune components, providing targeted treatment for autoimmune diseases.
While Rituxan does not cure autoimmune neurological conditions, it helps quiet the overactive immune response that contributes to disease activity, slowing progression and improving stability over time. The timeline for seeing results varies by condition and individual response. The first infusion takes effect within days as B-cells are depleted, but clinical improvements (e.g., reduced symptoms or disease activity) typically become noticeable over several weeks to months as inflammation decreases and the immune system stabilizes.
Like all medications, Rituxan can cause side effects. Common side effects include:
Serious Rituxan infusion side effects require immediate medical attention and include:
Your healthcare team at our infusion center will monitor you closely during and after each Rituxan infusion treatment to ensure your safety.
The cost of Rituxan infusion depends on several factors, including your insurance coverage and plan. Understanding the Rituxan infusion cost is important, and at Advanced Neurology Colorado, we are committed to helping patients receive treatment affordably and with minimal stress.
We work with most major commercial insurance providers in Colorado, including Aetna, Anthem, Blue Cross Blue Shield, Cigna, Humana, and UnitedHealthcare, along with Medicaid and Medicare. Our team ensures you receive maximum coverage for your Rituxan infusion therapy.
Our experienced team provides comprehensive support to make treatment more accessible:
Our infusion center is led by board-certified neurologists and experienced BSN-prepared Registered Nurses who specialize in infusion therapy for neurological disorders. Our team has advanced training and extensive experience managing patients with multiple sclerosis, myasthenia gravis, and neuropathy. Our healthcare providers understand the nuances of B-cell depleting therapies and how to optimize outcomes for each patient.
Our comprehensive approach also includes advanced diagnostic capabilities such as electromyography to accurately assess nerve and muscle function, ensuring your treatment plan is tailored to your specific condition.
We manage all insurance processes and guide patients through financial assistance options. Physician-owned infusion sites like Advanced Neurology Colorado's Infusion Center typically help patients achieve lower overall costs than hospital-based centers, making the Rituxan infusion cost more manageable for our patients.
Providing expert, compassionate care for 20+ years to individuals across Colorado with MS and other neurological conditions. Our decades of experience with Rituxan infusion protocol and other immunotherapies means we understand not only the clinical aspects of treatment but also the real-world impact on our patients' daily lives.
Non-Hodgkin’s Lymphoma (NHL)
B-cell acute leukemia (B-AL)
Chronic Lymphocytic Leukemia (CLL)
Rheumatoid arthritis (RA)
Granulomatosis with Polyangiitis (GPA) (Wegener’s Granulomatosis)
Microscopic Polyangiitis (MPA)
Pemphigus Vulgaris (PV)
Non-Hodgkin’s Lymphoma (NHL): Approved on November 26, 1997
B-cell acute leukemia (B-AL): Approved on February 10, 2006
Chronic Lymphocytic Leukemia (CLL): Approved on February 19, 2010
Rheumatoid arthritis (RA): Approved on February 28, 2006
Granulomatosis with Polyangiitis (GPA) (Wegener’s Granulomatosis): Approved on September 27, 2019
Microscopic Polyangiitis (MPA): Approved on September 27, 2019
Pemphigus Vulgaris (PV): Approved on June 7, 2018
Genentech
"Billing is transparent—no surprise charges like at my last neuro."
"MG crisis hero - Got me into the hospital for IVIG within 4 hours during a bulbar crisis. Her fellow even checked on me at midnight."
"I feel confident knowing I'm in capable hands and truly appreciate the thoughtful, attentive care Dr. Dasari provides. I highly recommend him to anyone seeking comprehensive and compassionate neurological care."
"Brutally honest - Wish she'd sugarcoat less, but her MG treatment plan stopped my hospitalizations. Clinical trials access is a plus."
“Dr. Yang is nothing but amazing! She has helped me so much with a diagnosis that moved my world upside down. She treats my almost daily migraines as well. She and her team will do what they can to get me the medication I need! She is very compassionate and kind!”
“Amazing. I have been with other Doctors at this practice as well but I had an amazing experience with Dr. Lackey specifically. Very attentive and friendly to work with! Highly recommend!”
"ALS guardian - Coordinates with my pulmonologist, PT, and speech therapist in one shared portal. Her ALS Functional Rating Scale checks keep us proactive."
"The MA Jess noticed I was anxious and brought me a weighted blanket. Above and beyond!"
"The only neurology clinic I’ve been to where you don’t feel like just a number."
"ANC’s telehealth option saved me a 2-hour drive. Seamless tech setup!"
"Spotless floors, sanitizer everywhere, and masks required. Felt very safe."
"ANC runs like a well-oiled machine. Appointments start on time, and the staff remembers me every visit."
“Dr. Dasari has been a God-send for my MS. He is incredibly knowledgeable and makes me feel heard. He allocates his time for me as a patient and I know I couldn’t manage this disease without him!”
"Migraine magician - Botox + Nurtec combo cut my headache days from 25/month to 4. His headache diary app makes tracking effortless."
"No-nonsense. Dr. Dasari's neuropathy staging system helped us prioritize treatments."
"Courtney Weir is an amazing medical professional! She is thorough and addresses all my questions. Each visit she remembers not only me, but asks about my family - above and beyond client care. I love having her, best provider by far! Can't recommend her enough."
“Amazing. I have been with other Doctors at this practice as well but I had an amazing experience with Dr. Lackey specifically. Very attentive and friendly to work with! Highly recommend!”
"No-nonsense. Dr. Dasari's neuropathy staging system helped us prioritize treatments."
"Migraine magician - Botox + Nurtec combo cut my headache days from 25/month to 4. His headache diary app makes tracking effortless."
“Dr. Dasari has been a God-send for my MS. He is incredibly knowledgeable and makes me feel heard. He allocates his time for me as a patient and I know I couldn’t manage this disease without him!”
"Brutally honest - Wish she'd sugarcoat less, but her MG treatment plan stopped my hospitalizations. Clinical trials access is a plus."
"MG crisis hero - Got me into the hospital for IVIG within 4 hours during a bulbar crisis. Her fellow even checked on me at midnight."
"ALS guardian - Coordinates with my pulmonologist, PT, and speech therapist in one shared portal. Her ALS Functional Rating Scale checks keep us proactive."
“Dr. Yang is nothing but amazing! She has helped me so much with a diagnosis that moved my world upside down. She treats my almost daily migraines as well. She and her team will do what they can to get me the medication I need! She is very compassionate and kind!”
"Spotless floors, sanitizer everywhere, and masks required. Felt very safe."
"Courtney Weir is an amazing medical professional! She is thorough and addresses all my questions. Each visit she remembers not only me, but asks about my family - above and beyond client care. I love having her, best provider by far! Can't recommend her enough."
"I feel confident knowing I'm in capable hands and truly appreciate the thoughtful, attentive care Dr. Dasari provides. I highly recommend him to anyone seeking comprehensive and compassionate neurological care."
"The MA Jess noticed I was anxious and brought me a weighted blanket. Above and beyond!"
"Billing is transparent—no surprise charges like at my last neuro."
"ANC’s telehealth option saved me a 2-hour drive. Seamless tech setup!"
"The only neurology clinic I’ve been to where you don’t feel like just a number."
"ANC runs like a well-oiled machine. Appointments start on time, and the staff remembers me every visit."
“Amazing. I have been with other Doctors at this practice as well but I had an amazing experience with Dr. Lackey specifically. Very attentive and friendly to work with! Highly recommend!”
"No-nonsense. Dr. Dasari's neuropathy staging system helped us prioritize treatments."
"Migraine magician - Botox + Nurtec combo cut my headache days from 25/month to 4. His headache diary app makes tracking effortless."
“Dr. Dasari has been a God-send for my MS. He is incredibly knowledgeable and makes me feel heard. He allocates his time for me as a patient and I know I couldn’t manage this disease without him!”
"Brutally honest - Wish she'd sugarcoat less, but her MG treatment plan stopped my hospitalizations. Clinical trials access is a plus."
"MG crisis hero - Got me into the hospital for IVIG within 4 hours during a bulbar crisis. Her fellow even checked on me at midnight."
"ALS guardian - Coordinates with my pulmonologist, PT, and speech therapist in one shared portal. Her ALS Functional Rating Scale checks keep us proactive."
“Dr. Yang is nothing but amazing! She has helped me so much with a diagnosis that moved my world upside down. She treats my almost daily migraines as well. She and her team will do what they can to get me the medication I need! She is very compassionate and kind!”
"Spotless floors, sanitizer everywhere, and masks required. Felt very safe."
"Courtney Weir is an amazing medical professional! She is thorough and addresses all my questions. Each visit she remembers not only me, but asks about my family - above and beyond client care. I love having her, best provider by far! Can't recommend her enough."
"I feel confident knowing I'm in capable hands and truly appreciate the thoughtful, attentive care Dr. Dasari provides. I highly recommend him to anyone seeking comprehensive and compassionate neurological care."
"The MA Jess noticed I was anxious and brought me a weighted blanket. Above and beyond!"
"Billing is transparent—no surprise charges like at my last neuro."
"ANC’s telehealth option saved me a 2-hour drive. Seamless tech setup!"
"The only neurology clinic I’ve been to where you don’t feel like just a number."
"ANC runs like a well-oiled machine. Appointments start on time, and the staff remembers me every visit."
“Amazing. I have been with other Doctors at this practice as well but I had an amazing experience with Dr. Lackey specifically. Very attentive and friendly to work with! Highly recommend!”
"No-nonsense. Dr. Dasari's neuropathy staging system helped us prioritize treatments."
"Migraine magician - Botox + Nurtec combo cut my headache days from 25/month to 4. His headache diary app makes tracking effortless."
“Dr. Dasari has been a God-send for my MS. He is incredibly knowledgeable and makes me feel heard. He allocates his time for me as a patient and I know I couldn’t manage this disease without him!”
"Brutally honest - Wish she'd sugarcoat less, but her MG treatment plan stopped my hospitalizations. Clinical trials access is a plus."
"MG crisis hero - Got me into the hospital for IVIG within 4 hours during a bulbar crisis. Her fellow even checked on me at midnight."
"ALS guardian - Coordinates with my pulmonologist, PT, and speech therapist in one shared portal. Her ALS Functional Rating Scale checks keep us proactive."
“Dr. Yang is nothing but amazing! She has helped me so much with a diagnosis that moved my world upside down. She treats my almost daily migraines as well. She and her team will do what they can to get me the medication I need! She is very compassionate and kind!”
"Spotless floors, sanitizer everywhere, and masks required. Felt very safe."
"Courtney Weir is an amazing medical professional! She is thorough and addresses all my questions. Each visit she remembers not only me, but asks about my family - above and beyond client care. I love having her, best provider by far! Can't recommend her enough."
"I feel confident knowing I'm in capable hands and truly appreciate the thoughtful, attentive care Dr. Dasari provides. I highly recommend him to anyone seeking comprehensive and compassionate neurological care."
"The MA Jess noticed I was anxious and brought me a weighted blanket. Above and beyond!"
"Billing is transparent—no surprise charges like at my last neuro."
"ANC’s telehealth option saved me a 2-hour drive. Seamless tech setup!"
"The only neurology clinic I’ve been to where you don’t feel like just a number."
"ANC runs like a well-oiled machine. Appointments start on time, and the staff remembers me every visit."
